K-RAS anticorps (AA 1-189)
Aperçu rapide pour K-RAS anticorps (AA 1-189) (ABIN7114805)
Antigène
Voir toutes K-RAS (KRAS) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-189
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Fonction
- KRAS antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: 1-189aa
Immunogen: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:1000, IHC: 1:50 - 1:200, IP: 1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- K-RAS (KRAS) (GTPase Kras (KRAS))
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Autre désignation
- KRAS
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Sujet
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Synonyms: GTPase KRas|K-Ras 2|Ki-Ras|c-K-ras|c-Ki-ras|GTPase KRas, N-terminally processed|KRAS|KRAS2|RASK2
Background: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation(PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes(TSGs) in colorectal cancer(CRC) cells in a ZNF304-dependent manner(PubMed:24623306).
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Poids moléculaire
- 21 kDa
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ID gène
- 3845
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UniProt
- P01116
Antigène
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